Below are the top 50 programs on cable on Thursday, 4/21/22. Items of note include Full Frontal with Samantha Bee on TBS, Top Chef on Bravo, and Atlanta on FX.
(Note: Click the names of the shows written in purple or blue to be taken to their pages in the TV Ratings Guide Cable Database.)
Show | Network | 18-49 Viewers | Viewers (mil.) |
| NBA Playoffs: Warriors v. Nuggets | TNT | 1.25 | 3.70 |
| NBA Playoffs: Grizzlies v. Timberwolves | TNT | 1.10 | 3.20 |
| Inside the NBA Playoffs | TNT | 0.52 | 1.49 |
| NBA Playoffs Pre-Game | TNT | 0.28 | 0.84 |
| Tucker Carlson Tonight | Fox News | 0.25 | 3.41 |
| Top Chef | Bravo | 0.23 | 0.74 |
| The Five | Fox News | 0.23 | 3.51 |
| Hannity | Fox News | 0.20 | 2.89 |
| Windy City Rehab | HGTV | 0.19 | 1.23 |
| Flip or Flop | HGTV | 0.18 | 1.09 |
| The Ingraham Angle | Fox News | 0.18 | 2.14 |
| Flip or Flop | HGTV | 0.18 | 1.06 |
| Special Report with Bret Baier | Fox News | 0.17 | 2.55 |
| NBA Playoffs: Mavericks v. Jazz | NBA | 0.17 | 0.42 |
| Gutfeld! | Fox News | 0.16 | 1.88 |
| Nightwatch | A&E | 0.16 | 0.69 |
| The Faulkner Focus | Fox News | 0.15 | 1.82 |
| House Hunters | HGTV | 0.15 | 1.20 |
| Outnumbered | Fox News | 0.15 | 1.68 |
| Siesta Key | MTV | 0.15 | 0.28 |
| The Faulkner Focus | Fox News | 0.15 | 1.54 |
| House Hunters International | HGTV | 0.15 | 1.14 |
| Pardon the Interruption | ESPN | 0.15 | 0.60 |
| Outnumbered | Fox News | 0.14 | 1.67 |
| Jesse Watters Primetime | Fox News | 0.14 | 2.37 |
| Restaurant Impossible | Food | 0.13 | 0.74 |
| First take | ESPN | 0.14 | 0.44 |
| Swamp People | History | 0.14 | 1.08 |
| Fox & Friends | Fox News | 0.13 | 1.44 |
| Fox & Friends | Fox News | 0.13 | 1.89 |
| America's Newsroom | TBS | 0.13 | 1.88 |
| Rat in the Kitchen | TBS | 0.13 | 0.47 |
| America's Newsroom | Fox News | 0.12 | 2.05 |
| Get Up | ESPN | 0.12 | 0.39 |
| NBA Today | ESPN | 0.12 | 0.35 |
| Your World with Neil Cavuto | Fox News | 0.12 | 1.56 |
| Beat Bobby Flay | Food | 0.12 | 0.65 |
| Anderson Cooper 360 | CNN | 0.11 | 0.82 |
| Erin Burnett OutFront | CNN | 0.11 | 0.81 |
| Sportscenter | ESPN | 0.11 | 0.29 |
| Fox News @ Night | Fox News | 0.11 | 0.93 |
| Fox & Friends | Fox News | 0.11 | 1.06 |
| Sportscenter | ESPN | 0.11 | 0.38 |
| This Just In | ESPN | 0.11 | 0.29 |
| Dr. Pimple Popper: Supersized | TLC | 0.11 | 0.69 |
| CNN Tonight | CNN | 0.10 | 0.68 |
| The Rachel Maddow Show | MSNBC | 0.10 | 2.16 |
| NFL Live | ESPN | 0.10 | 0.35 |
| Around the Horn | ESPN | 0.10 | 0.38 |
| Ex on the Beach | MTV | 0.10 | 0.21 |
| Highlights Below the Chart: | |||
| The Situation Room | CNN | 0.09 | 0.65 |
| Don Lemon Tonight | CNN | 0.08 | 0.61 |
| Atlanta | FX | 0.08 | 0.20 |
| The Daily Show | Comedy Central | 0.08 | 0.34 |
| Last Word with Lawrence O'Donnell | MSNBC | 0.06 | 1.44 |
| Side Hustle | Nickelodeon | 0.06 | 0.25 |
| Deadline: White House | MSNBC | 0.05 | 1.12 |
| Fairly Odder | Nickelodeon | 0.05 | 0.20 |
| Full Frontal with Samantha Bee | TBS | 0.04 | 0.21 |
| 11th Hour with Stephanie Ruhle | MSNBC | 0.04 | 0.90 |
| Morning Joe | MSNBC | 0.04 | 0.83 |
| All In with Chris Hayes | MSNBC | 0.04 | 1.13 |
| The ReidOut | MSNBC | 0.04 | 1.01 |
